ZNF622 antibody
Quick Overview for ZNF622 antibody (ABIN7127125)
Target
See all ZNF622 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF622 (zinc-finger protein 622), also known as ZPR9 (zinc-fingerlike protein 9), is a 477 amino acid protein that localizes to both the nucleus and the cytoplasm. Expressed in liver, spleen, lung, kidney and brain, ZNF622 is thought to activate the bound transcription factor B-Myb and, through this activation, may play a role in embryonic development. ZNF622 contains two U1-type zinc fingers and exists as either a homodimer or a heterodimer that can be phosphorylated by MELK (maternal embryonic leucine zipper kinase). Overexpression of ZNF266 may be associated with liver metastases, carcinomatoses and colorectal carcinomas.
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Cross-Reactivity (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human ZNF622 protein
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Isotype
- IgG2a
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Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- ZNF622 (Zinc Finger Protein 622 (ZNF622))
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Alternative Name
- ZNF622
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Background
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MGC108936, Zinc finger protein 622, Zinc finger-like protein 9, ZNF622, ZPR9,ZNF622 / ZPR9 (Transcription Factor)
Cellular localisation: Cytoplasm. Nucleus. -
Molecular Weight
- 52kDa
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Gene ID
- 90441, 60300
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UniProt
- Q969S3
Target
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